Ulcerating Herpes Simplex Infection

Neonatal herpes simplex infection.

Tremendous advances have occurred over the past 30 years in the diagnosis and management of neonatal herpes simplex virus (HSV) disease. Mortality in patients with disseminated disease has decreased from 85 to 29%, and that in patients with central nervous system (CNS) disease has decreased from 50 to 4%. Morbidity has been improved more modestly: the proportion of patients with disseminated di...

Detection of Herpes Simplex Virus Infection in Cerebrospinal Fluid

ABSTRACT        Background and Objective: Herpes simplex encephalitis is a life-threatening consequence of the central nervous system (CNS) infection with Herpes simplex virus (HSV). Although it is a rare disease, mortality rates reach 70% in the absence of therapy and only a minority of individuals can return to normal function. The aim of this study was to d...

Neonatal herpes simplex virus infection

Neonatal herpes simplex virus (HSV) infections may be caused by either herpes simplex virus type-1 (HSV-1) or herpes simplex virus type-2 (HSV-2). In the United States, HSV-2 is responsible for 75% of genital and neonatal infections, while HSV-1 causes the rest. HSV-1 more commonly affects the oropharynx, the eyes and the central nervous system.1,2 It is estimated that 20 to 30% of sexually act...

[Diagnosis of herpes simplex virus infection].

The utility of the indirect immunofluorescent antibody (IFA) technique for diagnosis of herpes simplex virus (HSV) infection was examined by testing specimens for this agent from 31 patients with encephalitis or meningitis, 17 with conjunctivitis, 19 with genital disease, and 1 with genital disease and meningitis. Brain biopsy tissue from four patients with encephalitis was positive by IFA and ...

Congenital oesophageal stenosis and herpes simplex infection.